The SiSCR has recently published an article ‘Dual Small-Molecule Targeting of SMAD Signaling Stimulates Human Induced Pluripotent Stem Cells toward Neural Lineages’
To provide an alternative renewable cell source for cell-based transplantation and as study models for neurological diseases, our group generated induced pluripotent stem cells from human dermal fibroblasts and then differentiated them into neural progenitor cells and mature neurons by dual SMAD signaling inhibitors