Sudjit Luanpitpong received her B.Sc. in Pharmacy and Ph.D. in Pharmaceutical Technology from Chulalongkorn University. In 2009, she joined Prof. Yon Rojasakul’s laboratory in the Health Sciences Center and Mary Babb Randolph Cancer Center, West Virginia University, USA as a Research Scholar to fulfill her research training through the Royal Golden Jubilee scholarship program. In 2011, she received her Ph.D. and continued her work at the West Virginia University as a Research Assistant Professor. Her research interest is in the area of cellular and molecular mechanisms of gene regulation and targeted therapy for cancer. Her work demonstrated the role of cancer stem cells in multistage of cancer from carcinogenesis to metastasis. In 2014, she returned to Thailand to join Prof. Surapol Issaragrisil’s laboratory at the SiSCR to pursue her interest in targeting cancer stem cells in cancer therapeutic discovery and development.

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  1. Luanpitpong S, Wang L, Manke A, Castranova V, Yang Y, and Rojanasakul Y. 2014. Induction of stem-like cells with fibrogenic properties by carbon nanotubes and its role in fibrogenesis. Nano Lett. 14:3110-3116.

  2. Luanpitpong S, Wang L, Castranova V, and Rojanasakul Y. 2014. Induction of stem-like cells with malignant properties by chronic exposure of human lung epithelial cells to single-walled carbon nanotubes. Part Fibre Toxicol. 11:22.

  3. Luanpitpong S, Wang L, and Rojanasakul Y. 2014. The effects of carbon nanotubes on lung and dermal cellular behaviors. Nanomedicine 9:895-912.

  4. Luanpitpong S*, Wang L, Castranova V, and Rojanasakul Y. 2014. Caveolin-1 regulates p53 inactivation and stem-like induction of carbon nanotube-driven lung tumorigenesis. Oncotarget 5:3541-3554.

  5. Talbott SJ*, Luanpitpong S*, Stehlik C, Wang L, and Rojanasakul Y. 2014. S-nitrosylation of FLICE inhibitory protein determines its interaction with RIP1 and activation of NF-kB. Cell Cycle 13:1948-1957.

  6. Manke A, Luanpitpong S, and Rojanasakul Y. 2014. Potential occupational risks associated with pulmonary toxicity of carbon nanotubes. Occup Med Health Aff. 2:165.

  7. Manke A, Luanpitpong S, Dong C, Wang L, He X, Batteli L, Derk R, Stueckle T, Porter D, Sager T, Gou H, Dinu CZ, Wu N, Mercer R, and Rojanasakul Y. Effect of fiber length on carbon nanotube-induced fibrogenesis. Int J Mol Sci. 15:7444-7461.

  8. Luanpitpong S, Chanvorachote P, Stehlik C, Tse W, Callery PS, Wang L, and Rojanasakul Y. 2013. Regulation of apoptosis by Bcl-2 cysteine oxidation in human lung epithelial cells. Mol Biol Cell. 24:858-869.

  9. Halim H, Luanpitpong S, and Chanvorachote P. 2012. Acquisition of anoikis resistance up-regulates caveolin-1 expression in human non-small cell lung cancer cells. Anticancer Res. 32:1649-1658.

  10. Chanvorachote P, Luanpitpong S, Chunhacha P, Promden W, and Sriurunpong V. 2012. Expression of CA125 and cisplatin susceptibility of pleural effusion-derived human lung cancer cells from Thai patient. Oncol Lett. 4, 252.

  11. Medan D*, Luanpitpong S*, Azad N, Wang L, Lu Y, Davis ME, Jiang BH, Barnett JB, Guo L, and Rojanasakul Y. 2012. Malignant transformation and tumorigenesis of chromium (VI)-transformed lung cells and their inhibition by Bcl-2 knockdown. PLoS ONE 7:e37045.

  12. Luanpitpong S, Chanvorachote P, Nimmannit U, Leonard SS, Stehlik C, and Rojanasakul Y. 2012. Mitochondrial superoxide mediates doxorubicin-induced apoptosis through ERK signaling and Bcl-2 ubiquitination in human keratinocytes. Biochem Pharmacol. 83:1643-1654.

  13. Luanpitpong S, Iyer AKV, Azad N, Wang L, and Rojanasakul Y. 2012. Nitrosothiol signaling in anoikis resistance and cancer metastasis. For Immunopathol Dis Therap. 3:141-154.

  14. Wang L*, Luanpitpong S*, Castranova V, Tse W, Lu Y, Pongrakhananon V, and Rojanasakul Y. 2011. Carbon nanotubes induce malignant transformation and tumorigenesis of human lung epithelial cells. Nano Lett. 11:2796-2803.

  15. Luanpitpong S, Nimmannit U, Chanvorachote P, Leonard SS, Pongrakhananon V, Wang L, and Rojanasakul Y. 2011. Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism. Apoptosis 16:769-782.

  16. Luanpitpong S, Talbott SJ, Rojanasakul Y, Nimmannit U, Pongrakhananon V, Wang L, and Chanvorachote P. 2011. Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1. J Biol Chem. 285:38832-38840.

  17. Luanpitpong S, Nimmannit U, Pongrakhananon V, and Chanvorachote P. 2011. Emblica (Phyllanthus emblica Linn.) fruit extract promotes proliferation in dermal papilla cells of human hair follicle. Res J Med Plant. 5:95-100.

  18. Luanpitpong S and Rojanasakul Y. Chemotherapy-induced alopecia. In: Cancer Treatment/Book 2, Mohan R (ed.), Intech Publisher, 2011.

  19. Luanpitpong S and Rojanasakul Y. Transdermal drug delivery. In: Basic Physical Pharmacy. Ma JKH and Hadzija B (eds.), Jones & Bartlett Learning, 2011.

  20. Luanpitpong S and Rojanasakul Y. Delivery of biotechnology drugs. In: Basic Physical Pharmacy. Ma JKH and Hadzija B (eds.), Jones & Bartlett Learning, 2011.

  21. Pongrakhananon V, Nimmannit U, Luanpitpong S, Rojanasakul Y, and Chanvorachote P. 2010. Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation. Apoptosis 15:574- 585.

  22. Chanvorachote P, Pongrakhananon V, Luanpitpong S, Chanvorachote B, Wannachaiyasit S, and Nimmannit U. 2009. Type I pro-collagen promoting and anti-collagenase activities of Phyllanthus emblica extract in mouse fibroblasts. J Cos Sci. 60: 395-403.

  23. Chanvorachote P, Pongrakhananon V, Wannachaiyasit S, Luanpitpong S, Rojanasakul Y, and Nimmannit U. 2009. Curcumin sensitizes lung cancer cells to cisplatin-induced apoptosis through superoxide anion-mediated Bcl-2 degradation. Cancer Invest. 27:624-635.

  24. Luanpitpong S, Pongrakhananon V, Nimmannit U, and Chanvorachote P. 2008. Emblica extract prevents cisplatin-induced apoptosis in dermal papilla fibroblasts. S J Sci Technol. 30:627-633.